At-home treatment options for chronic obstructive pulmonary disease (COPD)
- Smoking cessation is the most effective intervention to slow disease progression and reduce mortality. Both behavioral support and pharmacotherapy (nicotine replacement, bupropion, varenicline) are recommended.[1-3]
-
Vaccinations against influenza and pneumococcus are essential to reduce the risk of respiratory infections and exacerbations.[1-3]
-
Avoidance of environmental exposures (e.g., air pollutants, occupational irritants) is advised to minimize symptom triggers.[1-2]
-
Pharmacologic therapy centers on inhaled bronchodilators: long-acting muscarinic antagonists (LAMA) and/or long-acting beta-agonists (LABA) are first-line for maintenance. Inhaled corticosteroids (ICS) are added for patients with frequent exacerbations. Proper inhaler technique and adherence are critical for efficacy.[1][3-5]
-
Long-term oxygen therapy (LTOT) is indicated for patients with severe resting hypoxemia (PaO₂ ≤ 55 mmHg or ≤ 60 mmHg with evidence of tissue hypoxia) and should be administered for ≥15 hours/day.[3-4]

Used under license from The New England Journal of Medicine.
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